Seminal Fluid Abnormalities

Sperm takes 3 months to produce and mature and there is often a 4 to 6 month delay between treatment of the man and resulting changes in the sperm. Since the evaluation of the woman may take several months, it is recommended that a comprehensive and accurate semen analysis be scheduled at the outset in order to evaluate the male partner. Treatment of the man can then occur at the same time as treatment of the woman and there will be no additional delay once the woman's treatment is completed.

The most common cause of male infertility is low sperm count. Absence of sperm in the semen is less common, affecting only 1% of all men and 10% to 15% of infertile men.

Causes of sperm count problems include:

• Hormonal problems in the testicles or pituitary gland. The pituitary gland releases hormones that stimulate the testicles to produce testosterone.
   
• Testicular injury or failure, either present at birth (congenital) or associated with radiation or toxic chemical exposure.
   
• Cancer treatment with certain kinds of chemotherapy or radiation.
   
• Antibodies that attack sperm and that also may be present in semen. Sperm antibodies sometimes develop when a man's sperm has been exposed to his immune system (outside of the testicles). This may happen after a vasectomy, an infection, or an injury to the testicles.
   
• Drug use (some prescription medications, and marijuana and tobacco use).
   
• Structural problems. These include:
  • A varicocele in the testicles.
  • Absence of a vas deferens (a birth defect that may be associated with the cystic fibrosis genes).
  • Retrograde ejaculation (the ejaculation of semen into the bladder rather than out through the penis).
  • Chromosomal problems (such as Klinefelter syndrome).
     
• Genetic problems.

Seminal fluid abnormality is among one of the factors which can cause male infertility.